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Sabrina

"What's the matter? I have to be a witch, I have to be a mortal, I have to be a teenager, and I have to be a girl all at the same time. That's the matter."

Sabrina Spellman is the main protagonist of the series. In the beginning of the show, she discovers that she is half-witch on her father's side. The adventures of the series show Sabrina as she deals with the day to day trials of being a teenager (and later, an adult) as well as being a witch.

In her sophomore year of high school, Sabrina's father, Edward, gets called away to the foreign services and her mother, Diana, goes on an archaelogical dig in Peru so she moves in with her zany aunts Zelda and Hilda in their Victorian house in Westbridge, a small suburb near Boston. At Westbridge High School, she befriends oddball Jenny, meets and develops a close relationship with football player Harvey Kinkle and becomes rivals with the popular captain of the cheerleading squad, Libby Chessler.

On her sixteenth birthday, Sabrina discovers that she is a witch. However, because she is a witch, she cannot communicate with her mortal mother for two years or else the later will turn into a ball of wax, on decree of the Witches Council. Additionally, her father, who is a witch, is in the Other Realm Foreign Services though she can talk to him through his picture in the Magic Book. Her aunts and their Familiar, Salem, a witch who tried to take over the world and was punished by being made into a cat, help her to slowly learn how to control her magical powers while she also tries to navigate through high school like a normal teenager. She slowly learns how to use these powers, starting with turning oranges, and even Libby, into pineapples. 

Source: SabrinaTheTeenageWitch.wikia.com